*Please note that gaskets, clamps, adapters, and pump are not included.
Filtration though a hydrophilic membrane with 0.22 micron and 1 micron pores is an important post-processing step of ultrasonic nano-emulsification with NanoStabilizer®-LT and NanoStabilizer®-LSO, which removes such particulate contamination as dust, large microorganisms, plant matter and titanium particles. In-line capsule filters are reusable and can typically handle several liters of product before having to be back-flushed with purified water to clear out the particulates retained by the membrane.
Lead time: 1 week
- Remove particulate contaminants (dust, large microorganisms, plant matter, titanium particles) from nanoemulsions.
- Filter nanoemulsions without rejecting any of the bioactive-containing oil droplets.
- Achieve higher product purity by eliminating particulate contamination.
After the nano-emulsification process is finished, connect the filter to a peristaltic pump and move the product through it at 0.25 - 0.5 L/min (adjust to avoid pressure buildup) into an autoclaved dark-glass container. Details can be found in NanoStabilizers® User Guides available at:
Q1. Do my nanoemulsion particle sizes change after filtration?
No. Filtration though a hydrophilic membrane does not change particle sizes in nanoemulsions.
Q2. What about my extract? Could it inadvertently get filtered out?
No. Capsule filters with 0.22 and 1 micron pores (without activated carbon) do not remove any active ingredients, extracts, excipients, carrier oils, preservatives or other formulation components from the nanoemulsions in which all droplets are smaller than 0.22 micron and 1 micron respectively. The hydrophilic character of the filter membrane ensures that the hydrophobic oil droplets have low affinity for the membrane material and will not stick to it as long as they can fit through the pores.
Q3. Will the titanium particles shed by the horn get filtered out?
Yes. Practically all titanium particles shed by the horn are easily removed by filtration. The graph below shows the size distribution of these particles determined by Laser Diffraction (Mictrotrac Analyzer S3500). Since all particles in the distribution are larger than 890 nm, passing the nanoemulsion through a filter with 1 micron pores removes practically all of the titanium. This was was confirmed by ultra sensitive measurements by Inductively Coupled Plasma Mass Spectrometry (Agilent ICP-MS 7500).
Q4 Do I need to filter my nanoemulsion even if there is no visible titanium contamination?
Yes. Filtering your final nanoemulsion is important, not only for removing titanium particles, but also to remove any other particulates, such as dust, large microorganisms and plant matter.
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